FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term protein-containing complex assembly ID (Ontology) GO:0065003 (Gene Ontology)
Definition The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.
Also Known As "cellular protein complex assembly"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       1
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 protein-containing complex assembly (all annotations which use CV term, excluding "NOT" statements)       1      1
     involved_in | protein-containing complex assembly       --       1
Spanning Tree (Parents/Children)
Only view relationship: 
cellular component organization
 |__cellular component assembly______________
 |__protein-containing complex organization__|
cellular component biogenesis                |
 |__cellular component assembly______________|
                                             protein-containing complex assembly  643 rec.
                                              |__activation of transmembrane receptor protein tyrosine kinase activity
                                              |__AIM2 inflammasome complex assembly
                                              |   |__regulation of AIM2 inflammasome complex assembly(+)
                                              |__anaphase-promoting complex assembly
                                              |__apoptosome assembly
                                              |   |__regulation of apoptosome assembly(+)
                                              |__Atg1/ULK1 kinase complex assembly 1 rec.
                                              |   |__regulation of Atg1/ULK1 kinase complex assembly(+) 1 rec.
                                              |__axonemal dynein complex assembly 30 rec.
                                              |   |__inner dynein arm assembly 7 rec.
                                              |   |__outer dynein arm assembly 13 rec.
                                              |__beta-catenin destruction complex assembly
                                              |__beta-catenin-TCF complex assembly
                                              |   |__regulation of beta-catenin-TCF complex assembly(+)
                                              |__canonical inflammasome complex assembly
                                              |   |__CARD8 inflammasome complex assembly
                                              |   |__NLRP1 inflammasome complex assembly
                                              |   |__NLRP3 inflammasome complex assembly(+)
                                              |   |__NLRP6 inflammasome complex assembly
                                              |__chaperone-mediated autophagy translocation complex assembly
                                              |__chaperone-mediated protein complex assembly 6 rec.
                                              |   |__regulation of chaperone-mediated protein complex assembly(+)
                                              |__ciliary centrin arm assembly
                                              |__ciliary necklace assembly
                                              |__ciliary transition fiber assembly
                                              |__clathrin coat assembly 3 rec.
                                              |   |__clathrin coat assembly involved in endocytosis
                                              |   |__clathrin coating of Golgi vesicle(+)
                                              |   |__regulation of clathrin coat assembly(+)
                                              |__COP9 signalosome assembly 2 rec.
                                              |__COPII vesicle coating 4 rec.
                                              |   |__regulation of COPII vesicle coating 3 rec.
                                              |__cytochrome complex assembly 37 rec.
                                              |   |__cytochrome b6f complex assembly
                                              |   |__cytochrome c-heme linkage
                                              |   |__peroxidase-heme linkage
                                              |   |__protein-heme P460 linkage
                                              |   |__respiratory chain complex III assembly(+) 10 rec.
                                              |   |__respiratory chain complex IV assembly(+) 27 rec.
                                              |__death-inducing signaling complex assembly
                                              |   |__regulation of death-inducing signaling complex assembly(+)
                                              |   |__TRAIL death-inducing signaling complex assembly
                                              |__dense core granule priming 1 rec.
                                              |__DNA repair complex assembly 3 rec.
                                              |   |__DNA recombinase assembly(+) 3 rec.
                                              |   |__DNA recombinase mediator complex assembly(+)
                                              |__dosage compensation complex assembly 2 rec.
                                              |__Dsc E3 ubiquitin ligase complex assembly
                                              |__ESCRT complex assembly
                                              |   |__ESCRT III complex assembly
                                              |__eukaryotic translation initiation factor 2 complex assembly
                                              |__eukaryotic translation initiation factor 2B complex assembly
                                              |__eukaryotic translation initiation factor 3 complex assembly
                                              |__eukaryotic translation initiation factor 4F complex assembly 3 rec.
                                              |   |__regulation of eukaryotic translation initiation factor 4F complex assembly(+) 3 rec.
                                              |__exocyst assembly
                                              |   |__regulation of exocyst assembly(+)
                                              |__exon-exon junction complex assembly 1 rec.
                                              |__FACT complex assembly 1 rec.
                                              |   |__regulation of FACT complex assembly(+) 1 rec.
                                              |__gamma-tubulin complex assembly
                                              |__Golgi membrane coat protein complex assembly
                                              |__Golgi membrane priming complex assembly
                                              |__heterotrimeric G-protein complex assembly
                                              |__integrator complex assembly 1 rec.
                                              |__integrin activation
                                              |   |__regulation of integrin activation(+)
                                              |__kinetochore assembly 13 rec.
                                              |   |__CENP-A containing chromatin assembly 6 rec.
                                              |   |__protein localization to kinetochore involved in kinetochore assembly 1 rec.
                                              |   |__regulation of kinetochore assembly(+)
                                              |__lateral cortical node assembly
                                              |__LinE complex assembly
                                              |__MBF transcription complex assembly
                                              |__MCM complex assembly
                                              |__mediator complex assembly
                                              |   |__regulation of mediator complex assembly(+)
                                              |__MHC protein complex assembly
                                              |   |__MHC class I protein complex assembly(+)
                                              |   |__MHC class Ib protein complex assembly(+)
                                              |   |__MHC class II protein complex assembly(+)
                                              |   |__peptide antigen assembly with MHC protein complex
                                              |__mitochondrial outer membrane translocase complex assembly 3 rec.
                                              |__mitochondrial respiratory chain complex assembly 82 rec.
                                              |   |__mitochondrial proton-transporting ATP synthase complex assembly 7 rec.
                                              |   |__mitochondrial respirasome assembly 5 rec.
                                              |   |__mitochondrial respiratory chain complex I assembly 30 rec.
                                              |   |__mitochondrial respiratory chain complex II assembly 6 rec.
                                              |   |__mitochondrial respiratory chain complex III assembly 10 rec.
                                              |   |__mitochondrial respiratory chain complex IV assembly 26 rec.
                                              |__mitotic checkpoint complex assembly
                                              |__Mre11 complex assembly
                                              |__mRNA cleavage and polyadenylation specificity factor complex assembly
                                              |__myosin filament assembly 7 rec.
                                              |   |__myosin II filament assembly(+) 3 rec.
                                              |   |__striated muscle myosin thick filament assembly(+) 1 rec.
                                              |__NAD(P)H dehydrogenase complex assembly
                                              |   |__NADH dehydrogenase complex (plastoquinone) assembly
                                              |__NADH dehydrogenase complex assembly 30 rec.
                                              |   |__mitochondrial respiratory chain complex I assembly 30 rec.
                                              |   |__NADH dehydrogenase complex (plastoquinone) assembly
                                              |__nodal receptor complex assembly
                                              |   |__regulation of nodal receptor complex assembly(+)
                                              |__non-canonical inflammasome complex assembly
                                              |__origin recognition complex assembly
                                              |__peptide antigen assembly with MHC protein complex
                                              |   |__peptide antigen assembly with MHC class I protein complex
                                              |   |__peptide antigen assembly with MHC class Ib protein complex
                                              |   |__peptide antigen assembly with MHC class II protein complex
                                              |__photosystem I assembly
                                              |__photosystem II assembly
                                              |   |__photosystem II oxygen evolving complex assembly
                                              |__podosome assembly
                                              |   |__regulation of podosome assembly(+)
                                              |__pore complex assembly 4 rec.
                                              |   |__nuclear pore complex assembly(+) 4 rec.
                                              |__post-translational protein targeting to membrane, docking
                                              |__proteasome assembly 15 rec.
                                              |   |__proteasome core complex assembly 1 rec.
                                              |   |__proteasome regulatory particle assembly 1 rec.
                                              |   |__regulation of proteasome assembly 3 rec.
                                              |__protein catenane formation
                                              |__protein complex oligomerization 18 rec.
                                              |   |__protein heterooligomerization(+)
                                              |   |__protein hexamerization
                                              |   |__protein homooligomerization(+) 15 rec.
                                              |   |__protein tetramerization(+) 5 rec.
                                              |   |__protein trimerization(+)
                                              |   |__regulation of protein oligomerization(+)
                                              |__protein polymerization 104 rec.
                                              |   |__actin filament polymerization(+) 54 rec.
                                              |   |__free ubiquitin chain polymerization(+)
                                              |   |__intermediate filament polymerization(+)
                                              |   |__microtubule polymerization(+) 50 rec.
                                              |   |__regulation of protein polymerization(+) 57 rec.
                                              |__protein-containing complex assembly involved in synapse maturation
                                              |__protein-DNA complex assembly 135 rec.
                                              |   |__DNA recombinase assembly(+) 3 rec.
                                              |   |__DNA replication preinitiation complex assembly(+) 2 rec.
                                              |   |__MCM complex loading
                                              |   |__nucleosome assembly 102 rec.
                                              |   |__nucleotide-excision repair, preincision complex assembly 1 rec.
                                              |   |__pre-replicative complex assembly(+) 2 rec.
                                              |   |__protein-DNA ISRE complex assembly
                                              |   |__shelterin complex assembly(+)
                                              |   |__telomere-telomerase complex assembly
                                              |   |__transcription preinitiation complex assembly(+) 22 rec.
                                              |__protein-DNA-RNA complex assembly
                                              |__protein-lipid complex assembly
                                              |   |__lipid antigen assembly with MHC class Ib protein complex
                                              |   |__lipid tube assembly(+)
                                              |   |__plasma lipoprotein particle assembly(+)
                                              |__protein-RNA complex assembly 160 rec.
                                              |   |__90S preribosome assembly
                                              |   |__assembly of large subunit precursor of preribosome(+) 1 rec.
                                              |   |__cis assembly of pre-catalytic spliceosome
                                              |   |__cytoplasmic U snRNP body assembly 1 rec.
                                              |   |__formation of cytoplasmic translation initiation complex 3 rec.
                                              |   |__formation of quadruple SL/U4/U5/U6 snRNP 14 rec.
                                              |   |__formation of translation initiation ternary complex(+) 1 rec.
                                              |   |__formation of translation preinitiation complex(+) 8 rec.
                                              |   |__generation of catalytic spliceosome for first transesterification step 1 rec.
                                              |   |__generation of catalytic spliceosome for second transesterification step(+) 2 rec.
                                              |   |__mRNA branch site recognition 8 rec.
                                              |   |__mRNA splice site recognition(+) 20 rec.
                                              |   |__ribosomal large subunit assembly(+) 21 rec.
                                              |   |__ribosomal small subunit assembly(+) 25 rec.
                                              |   |__RISC complex assembly 15 rec.
                                              |   |__RITS complex assembly
                                              |   |__small nucleolar ribonucleoprotein complex assembly(+) 7 rec.
                                              |   |__small-subunit processome assembly 6 rec.
                                              |   |__spliceosomal complex assembly(+) 40 rec.
                                              |   |__spliceosomal conformational changes to generate catalytic conformation(+) 4 rec.
                                              |   |__spliceosomal snRNP assembly(+) 38 rec.
                                              |   |__spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) 1 rec.
                                              |   |__telomerase holoenzyme complex assembly(+)
                                              |   |__trans assembly of SL-containing precatalytic spliceosome
                                              |__proton-transporting two-sector ATPase complex assembly 15 rec.
                                              |   |__proton-transporting ATP synthase complex assembly(+) 7 rec.
                                              |   |__proton-transporting V-type ATPase complex assembly(+) 8 rec.
                                              |__pyroptosome complex assembly
                                              |__radial spoke assembly
                                              |__regulation of protein-containing complex assembly 84 rec.
                                              |   |__negative regulation of protein-containing complex assembly(+) 24 rec.
                                              |   |__positive regulation of protein-containing complex assembly(+) 22 rec.
                                              |   |__regulation of AIM2 inflammasome complex assembly(+)
                                              |   |__regulation of apoptosome assembly(+)
                                              |   |__regulation of assembly of large subunit precursor of preribosome(+)
                                              |   |__regulation of Atg1/ULK1 kinase complex assembly(+) 1 rec.
                                              |   |__regulation of beta-catenin-TCF complex assembly(+)
                                              |   |__regulation of chaperone-mediated protein complex assembly(+)
                                              |   |__regulation of clathrin coat assembly(+)
                                              |   |__regulation of COPII vesicle coating 3 rec.
                                              |   |__regulation of death-inducing signaling complex assembly(+)
                                              |   |__regulation of DNA recombinase mediator complex assembly(+)
                                              |   |__regulation of eukaryotic translation initiation factor 4F complex assembly(+) 3 rec.
                                              |   |__regulation of exocyst assembly(+)
                                              |   |__regulation of FACT complex assembly(+) 1 rec.
                                              |   |__regulation of formation of translation initiation ternary complex(+) 1 rec.
                                              |   |__regulation of formation of translation preinitiation complex(+) 1 rec.
                                              |   |__regulation of high-density lipoprotein particle assembly(+)
                                              |   |__regulation of integrin activation(+)
                                              |   |__regulation of kinetochore assembly(+)
                                              |   |__regulation of mediator complex assembly(+)
                                              |   |__regulation of myosin II filament assembly(+) 1 rec.
                                              |   |__regulation of NLRP3 inflammasome complex assembly(+)
                                              |   |__regulation of nodal receptor complex assembly(+)
                                              |   |__regulation of podosome assembly(+)
                                              |   |__regulation of proteasome assembly 3 rec.
                                              |   |__regulation of protein oligomerization(+)
                                              |   |__regulation of protein polymerization(+) 57 rec.
                                              |   |__regulation of pseudohyphal septin ring assembly(+)
                                              |   |__regulation of ripoptosome assembly involved in necroptotic process(+)
                                              |   |__regulation of RNA polymerase II transcription preinitiation complex assembly(+) 3 rec.
                                              |   |__regulation of shelterin complex assembly(+)
                                              |   |__regulation of SNARE complex assembly(+) 8 rec.
                                              |   |__regulation of starch utilization system complex assembly(+)
                                              |   |__regulation of synaptic vesicle priming(+)
                                              |   |__regulation of telomerase catalytic core complex assembly(+)
                                              |   |__regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly(+) 1 rec.
                                              |   |__regulation of Wnt-Frizzled-LRP5/6 complex assembly(+)
                                              |__respiratory chain complex II assembly 6 rec.
                                              |   |__mitochondrial respiratory chain complex II assembly 6 rec.
                                              |__ribulose bisphosphate carboxylase complex assembly
                                              |__ripoptosome assembly
                                              |   |__ripoptosome assembly involved in extrinsic apoptotic signaling pathway
                                              |   |__ripoptosome assembly involved in necroptotic process(+)
                                              |__RNA polymerase I assembly 1 rec.
                                              |__RNA polymerase II core complex assembly 1 rec.
                                              |__RNA polymerase III assembly 1 rec.
                                              |__SAGA complex assembly 1 rec.
                                              |__SCF complex assembly 1 rec.
                                              |__septin ring assembly
                                              |   |__pseudohyphal septin ring assembly(+)
                                              |__signal complex assembly 1 rec.
                                              |__SNARE complex assembly 10 rec.
                                              |   |__regulation of SNARE complex assembly(+) 8 rec.
                                              |__sodium-translocating NADH-quinone reductase complex assembly
                                              |__SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition 3 rec.
                                              |__starch utilization system complex assembly
                                              |   |__regulation of starch utilization system complex assembly(+)
                                              |__steroid hormone receptor complex assembly
                                              |__synaptic vesicle priming 16 rec.
                                              |   |__regulation of synaptic vesicle priming(+)
                                              |__TCR signalosome assembly
                                              |__TORC1 complex assembly
                                              |__transcription factor TFIIIB complex assembly
                                              |__transforming growth factor beta receptor complex assembly
                                              |__tubulin complex assembly 9 rec.
                                              |__VCP-NPL4-UFD1 AAA ATPase complex assembly 1 rec.
                                              |   |__regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly(+) 1 rec.
                                              |__voltage-gated calcium channel complex assembly
                                              |__Wnt signalosome assembly
                                              |__Wnt-Frizzled-LRP5/6 complex assembly
                                              |   |__regulation of Wnt-Frizzled-LRP5/6 complex assembly(+)
                                              |__Y-shaped link assembly
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Is a cellular component assembly
protein-containing complex organization
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Synonyms
  • "cellular macromolecule complex assembly" RELATED
    "cellular protein complex assembly" EXACT
    "cellular protein-containing complex assembly" RELATED
    "chaperone activity" RELATED
    "macromolecular complex assembly" RELATED
    "macromolecule complex assembly" RELATED
    "protein complex assembly" RELATED
    "protein complex formation" RELATED
Secondary IDs
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