FB2025_05 , released December 11, 2025

General Information
Term	nucleotide-binding oligomerization domain containing 2 signaling pathway	ID (Ontology)	GO:0070431 (Gene Ontology)
Definition	The series of molecular signals initiated by the binding of a ligand (such as a bacterial peptidoglycan) to a cytoplasmic nucleotide-binding oligomerization domain containing 2 (NOD2) protein receptor, and ending with regulation of a downstream cellular process.[ PubMed:17944960 PubMed:18585455 ]
Also Known As	"NOD2 signaling pathway" ; "nucleotide-binding oligomerization domain containing 2 signalling pathway"
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Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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General Information

Term

nucleotide-binding oligomerization domain containing 2 signaling pathway

ID (Ontology)

GO:0070431 (Gene Ontology)

Definition

The series of molecular signals initiated by the binding of a ligand (such as a bacterial peptidoglycan) to a cytoplasmic nucleotide-binding oligomerization domain containing 2 (NOD2) protein receptor, and ending with regulation of a downstream cellular process.[ PubMed:17944960 PubMed:18585455 ]

Also Known As

"NOD2 signaling pathway" ; "nucleotide-binding oligomerization domain containing 2 signalling pathway"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

No relevant statements available

cytoplasmic pattern recognition receptor signaling pathway |__nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway |__nucleotide-binding oligomerization domain containing 2 signaling pathway |__regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway |__negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway |__positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

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Is a	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
Part of
Synonyms & Secondary IDs
Synonyms
	"NOD2 signaling pathway" EXACT "nucleotide-binding oligomerization domain containing 2 signalling pathway" EXACT
Secondary IDs

External Crossreferences & Linkouts

Spanning Tree View Settings

Parents/Children
View Depth

Relationships

Is a

nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway

Part of

Synonyms & Secondary IDs

Synonyms

"NOD2 signaling pathway" EXACT
"nucleotide-binding oligomerization domain containing 2 signalling pathway" EXACT

Secondary IDs

External Crossreferences & Linkouts