FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term catalytic step 1 spliceosome ID (Ontology) GO:0071012 (Gene Ontology)
Definition A spliceosomal complex that is formed by the displacement of the two snRNPs from the precatalytic spliceosome; three snRNPs including U5 remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the associated snRNPs.[ PubMed:18322460 PubMed:19239890 ]
Also Known As "activated spliceosome"
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protein-containing complex
 |__catalytic complex_______________
nuclear protein-containing complex  |
 |__spliceosomal complex____________|
ribonucleoprotein complex           |
 |__spliceosomal complex____________|
                                    catalytic step 1 spliceosome  3 rec.
                                     |__U2-type catalytic step 1 spliceosome 3 rec.
                                     |__U12-type catalytic step 1 spliceosome
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Is a spliceosomal complex
catalytic complex
Part of
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Synonyms
  • "activated spliceosome" EXACT[ ISBN:0879695897 ISBN:0879697393 ]
    "mammalian spliceosomal complex B*" NARROW[ ISBN:0879695897 ISBN:0879697393 PubMed:19239890 ]
    "mammalian spliceosomal complex B2" NARROW[ ISBN:0879695897 ISBN:0879697393 ]
    "yeast spliceosomal complex A1" NARROW[ ISBN:0879695897 ISBN:0879697393 ]
Secondary IDs
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