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| Term | NF-kappaB complex | ID (Ontology) | GO:0071159 (Gene Ontology) |
| Definition | A protein complex that consists of a homo- or heterodimer of members of a family of structurally related proteins that contain a conserved N-terminal region called the Rel homology domain (RHD). In the nucleus, NF-kappaB complexes act as transcription factors. In unstimulated cells, NF-kappaB dimers are sequestered in the cytoplasm by IkappaB monomers; signals that induce NF-kappaB activity cause degradation of IkappaB, allowing NF-kappaB dimers to translocate to the nucleus and induce gene expression.[ ISBN:0849327946 ] | ||
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nucleus_____________________ protein-containing complex__| nuclear protein-containing complex |__NF-kappaB complex |__NF-kappaB p50/p65 complex |
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| Is a | nuclear protein-containing complex | ||
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