FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term CMG complex ID (Ontology) GO:0071162 (Gene Ontology)
Definition A protein complex that contains the GINS complex, Cdc45p, and the heterohexameric MCM complex, and that is involved in unwinding DNA during replication.[ PubMed:19228417 ]
Also Known As "unwindosome"
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       4
Genes (FBgn)  GO_CELLULAR_COMPONENT      11
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 CMG complex (all annotations which use CV term, excluding "NOT" statements)       1     11
     part_of | CMG complex       --      11
Spanning Tree (Parents/Children)
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nucleoplasm
 |__DNA replication preinitiation complex__
chromosome                                 |
 |__nuclear chromosome_____________________|
nuclear lumen                              |
 |__nuclear chromosome_____________________|
protein-DNA complex                        |
 |__DNA replication preinitiation complex__|
nuclear protein-containing complex         |
 |__DNA replication preinitiation complex__|
                                           CMG complex  12 rec.
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Is a DNA replication preinitiation complex
Part of nuclear chromosome
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