FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term mitotic spindle checkpoint signaling ID (Ontology) GO:0071174 (Gene Ontology)
Definition A signaling process that contributes to a mitotic cell cycle checkpoint that originates from the spindle and delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and oriented, the completion of anaphase until chromosomes are attached to the spindle, or mitotic exit and cytokinesis when the spindle does not form.
Also Known As "mitotic cell cycle spindle checkpoint" ; "mitotic spindle checkpoint" ; "signal transduction involved in mitotic cell cycle spindle checkpoint" (for all, see Synonyms field below)
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cell cycle checkpoint signaling
 |__mitotic cell cycle checkpoint signaling__
 |__spindle checkpoint signaling_____________|
negative regulation of mitotic cell cycle    |
 |__mitotic cell cycle checkpoint signaling__|
mitotic cell cycle process                   |
 |__mitotic cell cycle checkpoint signaling__|
                                             mitotic spindle checkpoint signaling  13 rec.
                                              |__mitotic spindle assembly checkpoint signaling 13 rec.
                                              |   |__regulation of mitotic cell cycle spindle assembly checkpoint(+) 4 rec.
                                              |__mitotic spindle orientation checkpoint signaling
                                              |__regulation of mitotic spindle checkpoint 4 rec.
                                                  |__regulation of mitotic cell cycle spindle assembly checkpoint(+) 4 rec.
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Is a mitotic cell cycle checkpoint signaling
spindle checkpoint signaling
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Synonyms
  • "mitotic cell cycle spindle checkpoint" EXACT
    "mitotic spindle checkpoint" EXACT
    "signal transduction involved in mitotic cell cycle spindle checkpoint" EXACT
    "signal transduction involved in mitotic spindle checkpoint" EXACT
    "topo II checkpoint" RELATED
    "topoisomerase II checkpoint" RELATED
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