General Information
Term	pheromone response MAPK cascade	ID (Ontology)	GO:0071507 (Gene Ontology)
Definition	A MAPK cascade containing at least the Fus3 MAP kinase. It starts with the activation of Ste20, a MAP4K, which activates Ste11, a MAP3K, which in turn activate Ste7, a MAP2K, which activates Fus3. The kinases in each tier phosphorylate and activate the kinases in the downstream tier. This MAPK cascade is triggered by a pheromone activating its G protein-coupled receptor, and results in cellular responses that lead to conjugation with cellular fusion.[ PubMed:17604854 ]
Also Known As	"conjugation with cellular fusion, MAPKKK cascade" ; "MAPK cascade involved in conjugation with cellular fusion" ; "MAPKKK cascade involved in conjugation with cellular fusion"
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General Information

Term

pheromone response MAPK cascade

ID (Ontology)

GO:0071507 (Gene Ontology)

Definition

A MAPK cascade containing at least the Fus3 MAP kinase. It starts with the activation of Ste20, a MAP4K, which activates Ste11, a MAP3K, which in turn activate Ste7, a MAP2K, which activates Fus3. The kinases in each tier phosphorylate and activate the kinases in the downstream tier. This MAPK cascade is triggered by a pheromone activating its G protein-coupled receptor, and results in cellular responses that lead to conjugation with cellular fusion.[ PubMed:17604854 ]

Also Known As

"conjugation with cellular fusion, MAPKKK cascade" ; "MAPK cascade involved in conjugation with cellular fusion" ; "MAPKKK cascade involved in conjugation with cellular fusion"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

No relevant statements available

response to pheromone triggering conjugation with cellular fusion
 |__pheromone-dependent signal transduction involved in conjugation with cellular fusion__
sexual reproduction                                                                       |
 |__conjugation with cellular fusion______________________________________________________|
signal transduction involved in positive regulation of conjugation with cellular fusion   |
 |__pheromone-dependent signal transduction involved in conjugation with cellular fusion__|
intracellular signaling cassette                                                          |
 |__MAPK cascade__________________________________________________________________________|
                                                                                         pheromone response MAPK cascade
                                                                                          |__regulation of pheromone response MAPK cascade
                                                                                              |__negative regulation of pheromone response MAPK cascade
                                                                                              |__positive regulation of pheromone response MAPK cascade

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Is a	MAPK cascade
Part of	conjugation with cellular fusion pheromone-dependent signal transduction involved in conjugation with cellular fusion
Synonyms & Secondary IDs
Synonyms
	"conjugation with cellular fusion, MAPKKK cascade" EXACT "Fus3 signaling cascade" NARROW[ PubMed:20880736 ] "MAPK cascade involved in conjugation with cellular fusion" EXACT "MAPK signaling in response to pheromone" RELATED[ PubMed:20880736 ] "MAPKKK cascade involved in conjugation with cellular fusion" EXACT "MAPKKK cascade involved in mating response" RELATED "pheromone MAPK module" RELATED[ PubMed:20880736 ]
Secondary IDs

External Crossreferences & Linkouts

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Is a

MAPK cascade

Part of

conjugation with cellular fusion
pheromone-dependent signal transduction involved in conjugation with cellular fusion

Synonyms & Secondary IDs

Synonyms

"conjugation with cellular fusion, MAPKKK cascade" EXACT
"Fus3 signaling cascade" NARROW[ PubMed:20880736 ]
"MAPK cascade involved in conjugation with cellular fusion" EXACT
"MAPK signaling in response to pheromone" RELATED[ PubMed:20880736 ]
"MAPKKK cascade involved in conjugation with cellular fusion" EXACT
"MAPKKK cascade involved in mating response" RELATED
"pheromone MAPK module" RELATED[ PubMed:20880736 ]

Secondary IDs

External Crossreferences & Linkouts