FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term polymeric IgA immunoglobulin complex ID (Ontology) GO:0071749 (Gene Ontology)
Definition A protein complex composed of two, three, or four monomeric IgA immunoglobulin complexes linked through both direct disulfide bonds and through disulfide binded monomers of J chain acting as a bridge. Each IgA monomer consists of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds. Dimeric IgA is sometimes complexed additionally with secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.[ ISBN:0781765196 PubMed:16362985 ]
Also Known As "pIgA antibody" ; "polymeric IgA antibody"
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immunoglobulin complex, circulating__
IgA immunoglobulin complex___________|
                                     IgA immunoglobulin complex, circulating
                                      |__polymeric IgA immunoglobulin complex
                                          |__dimeric IgA immunoglobulin complex
                                          |   |__secretory dimeric IgA immunoglobulin complex
                                          |__secretory IgA immunoglobulin complex
                                              |__secretory dimeric IgA immunoglobulin complex
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Is a IgA immunoglobulin complex, circulating
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Synonyms
  • "pIgA antibody" EXACT
    "pIgA1 antibody" NARROW
    "polymeric IgA antibody" EXACT
    "polymeric IgA1 antibody" NARROW
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