FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term protein activation cascade ID (Ontology) GO:0072376 (Gene Ontology)
Definition A sequential series of modifications to a set of proteins where the product of one reaction catalyzes the following reaction, ultimately leading to the generation of a mature protein. Modifications typically include proteolysis or covalent modification, and may also include binding events.
Also Known As "protein activation pathway" ; "protein activitory cascade"
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gene expression____________
protein metabolic process__|
                           protein maturation
                            |__protein activation cascade  29 rec.
                                |__blood coagulation, common pathway
                                |   |__regulation of blood coagulation, common pathway(+)
                                |__blood coagulation, extrinsic pathway
                                |   |__regulation of blood coagulation, extrinsic pathway(+)
                                |__blood coagulation, fibrin clot formation
                                |   |__blood coagulation, common pathway
                                |   |__blood coagulation, extrinsic pathway
                                |   |__blood coagulation, intrinsic pathway
                                |__blood coagulation, intrinsic pathway
                                |   |__regulation of blood coagulation, intrinsic pathway(+)
                                |__kinin cascade
                                |   |__plasma kallikrein-kinin cascade(+)
                                |   |__regulation of kinin cascade(+)
                                |   |__tissue kallikrein-kinin cascade(+)
                                |__regulation of protein activation cascade 5 rec.
                                |   |__negative regulation of protein activation cascade(+) 5 rec.
                                |   |__positive regulation of protein activation cascade(+)
                                |   |__regulation of blood coagulation, common pathway(+)
                                |   |__regulation of blood coagulation, extrinsic pathway(+)
                                |   |__regulation of blood coagulation, intrinsic pathway(+)
                                |   |__regulation of kinin cascade(+)
                                |   |__regulation of Toll receptor ligand protein activation cascade(+) 5 rec.
                                |__Toll receptor ligand protein activation cascade 29 rec.
                                    |__regulation of Toll receptor ligand protein activation cascade(+) 5 rec.
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Synonyms
  • "protein activation pathway" EXACT
    "protein activitory cascade" EXACT
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