FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term T-helper 17 cell lineage commitment ID (Ontology) GO:0072540 (Gene Ontology)
Definition The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 17 cell, a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17.
Also Known As "T-helper 17 cell fate commitment" ; "Th17 cell lineage commitment" ; "Th17 fate commitment"
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T-helper cell differentiation
 |__T-helper cell lineage commitment________________
 |__T-helper 17 cell differentiation________________|
CD4-positive, alpha-beta T cell lineage commitment  |
 |__T-helper cell lineage commitment________________|
T-helper 17 type immune response                    |
 |__T-helper 17 cell differentiation________________|
                                                    T-helper 17 cell lineage commitment
                                                     |__regulation of T-helper 17 cell lineage commitment
                                                         |__negative regulation of T-helper 17 cell lineage commitment
                                                         |__positive regulation of T-helper 17 cell lineage commitment
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Is a T-helper cell lineage commitment
Part of T-helper 17 cell differentiation
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Synonyms
  • "T-helper 17 cell fate commitment" EXACT
    "Th17 cell lineage commitment" EXACT
    "Th17 fate commitment" EXACT
Secondary IDs
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