FB2025_05 , released December 11, 2025

CV Term Report

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General Information
Term	cellular senescence	ID (Ontology)	GO:0090398 (Gene Ontology)
Definition	A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest.[ PubMed:28682291 ]
Comment
Links to External Ontologies
	QuickGO data AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
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Spanning Tree (Parents/Children)

response to stress
 |__cellular response to stress__
biological_process               |
 |__cellular process_____________|
cellular response to stimulus    |
 |__cellular response to stress__|
                                 cellular senescence  3 rec.
                                  |__oncogene-induced cell senescence
                                  |__regulation of cellular senescence 3 rec.
                                  |   |__negative regulation of cellular senescence 3 rec.
                                  |   |__positive regulation of cellular senescence
                                  |__stress-induced premature senescence
                                      |__oxidative stress-induced premature senescence

Spanning Tree View Settings
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Relationships
Is a	cellular process
Part of	cellular response to stress
Synonyms & Secondary IDs
Synonyms

Secondary IDs

External Crossreferences & Linkouts
	Reactome:R-HSA-2559583 "Cellular Senescence"