FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term endothelial tip cell fate specification ID (Ontology) GO:0097102 (Gene Ontology)
Definition The process involved in the specification of identity of an endothelial tip cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial tip cell is a specialized endothelial cell localized to the leading edge of an angiogenic sprout that senses extracellular signals and guides the directed growth of blood vessels.[ PubMed:21521739 ]
Also Known As "angiogenic tip cell fate specification"
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angiogenesis
 |__sprouting angiogenesis____________________________
blood vessel endothelial cell fate commitment         |
 |__blood vessel endothelial cell fate specification__|
endothelial cell fate specification                   |
 |__blood vessel endothelial cell fate specification__|
                                                      endothelial tip cell fate specification
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Is a blood vessel endothelial cell fate specification
Part of sprouting angiogenesis
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Synonyms
  • "angiogenic tip cell fate specification" EXACT
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