FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term centralspindlin complex ID (Ontology) GO:0097149 (Gene Ontology)
Definition A heterotetrameric protein complex playing a key role in the formation of the central spindle in mitosis. Made up of two molecules each of a mitotic kinesin (ZEN-4 in Caenorhabditis elegans or MKLP1 in mammals) and of two molecules each of a GTPase activating protein (GAP) factor (CYK-4 in Caenorhabditis elegans or MgcRacGAP in mammals).[ PubMed:11782313 PubMed:16236794 ]
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Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       4
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 Genes
 centralspindlin complex (all annotations which use CV term, excluding "NOT" statements)       4
     part_of | centralspindlin complex       4
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  protein-containing complex
   |__intracellular protein-containing complex
       |__centralspindlin complex  4 rec.
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Is a intracellular protein-containing complex
Part of mitotic spindle
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