FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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Term extrinsic apoptotic signaling pathway in absence of ligand ID (Ontology) GO:0097192 (Gene Ontology)
Definition The series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with withdrawal of a ligand from a cell surface receptor, and ends when the execution phase of apoptosis is triggered.[ PubMed:15044679 PubMed:20816705 ]
Also Known As "extrinsic apoptotic signalling pathway in absence of ligand"
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signal transduction
 |__signal transduction in absence of ligand__
cell surface receptor signaling pathway       |
 |__extrinsic apoptotic signaling pathway_____|
apoptotic signaling pathway                   |
 |__extrinsic apoptotic signaling pathway_____|
                                              extrinsic apoptotic signaling pathway in absence of ligand  1 rec.
                                               |__regulation of extrinsic apoptotic signaling pathway in absence of ligand 1 rec.
                                                   |__negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 1 rec.
                                                   |__positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
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Is a signal transduction in absence of ligand
extrinsic apoptotic signaling pathway
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Synonyms
  • "dependence receptor signaling pathway" RELATED
    "extrinsic apoptosis in absence of ligand" NARROW
    "extrinsic apoptotic signalling pathway in absence of ligand" EXACT
Secondary IDs
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Reactome:R-HSA-418889 "Caspase activation via Dependence Receptors in the absence of ligand"