FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term ripoptosome ID (Ontology) GO:0097342 (Gene Ontology)
Definition A protein complex whose core components are the receptor-interacting serine/threonine-protein kinases RIPK1 and RIPK3 (also called RIP1 and RIP3). Formation of the ripoptosome can induce an extrinsic apoptotic signaling pathway or a necroptotic signaling pathway. The composition of this protein complex may depend on several factors including nature of the signal, cell type and more.[ PubMed:22265414 PubMed:22274400 ]
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cytoplasm
 |__cytosol____________________
protein-containing complex     |
 |__catalytic complex__________|
cellular anatomical structure  |
 |__cytosol____________________|
                               ripoptosome
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Is a catalytic complex
Part of cytosol
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