FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term neurofibrillary tangle ID (Ontology) GO:0097418 (Gene Ontology)
Definition Intracellular mass of paired, helically wound protein filaments (also called PHF) lying in the cytoplasm of neuronal cell bodies and neuritic cell processes. Neurofibrillary tangles contain an abnormally phosphorylated form of a microtubule-associated protein, tau. The shape of these inclusions may resemble a flame or a star.
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  intracellular anatomical structure
   |__inclusion body
       |__neurofibrillary tangle
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Synonyms
  • "flame-shaped neurofibrillary tangle" NARROW
    "star-shaped neurofibrillary tangle" NARROW
Secondary IDs
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NIF_Subcellular:nlx_subcell_20090201
NIF_Subcellular:nlx_subcell_20090202
NIF_Subcellular:sao2409833926