FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term Rad6-Rad18 complex ID (Ontology) GO:0097505 (Gene Ontology)
Definition A ubiquitin ligase complex found to be involved in post-replicative bypass of UV-damaged DNA and UV mutagenesis. In S. cerevisiae, the complex contains the ubiquitin conjugating enzyme Rad6 and Rad18, a protein containing a RING finger motif and a nucleotide binding motif. The yeast Rad6-Rad18 heterodimer has ubiquitin conjugating activity, binds single-stranded DNA, and possesses single-stranded DNA-dependent ATPase activity.[ PubMed:9287349 ]
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intracellular protein-containing complex__
transferase complex_______________________|
                                          ubiquitin ligase complex
                                           |__Rad6-Rad18 complex
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