Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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| Term | PTEX complex | ID (Ontology) | GO:0097619 (Gene Ontology) |
| Definition | A protein complex that acts as a protein trafficking machinery and is responsible for the export of proteins across the parasitophorous (symbiont-containing) vacuolar membrane and into the human host cell. The PTEX complex is located in the vacuole membrane. It is ATP-powered, and comprises heat shock protein 101 (HSP101; a ClpA/B-like ATPase from the AAA+ superfamily, of a type commonly associated with protein translocons), a parasite protein termed PTEX150, and exported protein 2 (EXP2). EXP2 is the potential channel, as it is the membrane-associated component of the core PTEX complex. Two other proteins, PTEX88 and thioredoxin 2 (TRX2), were also identified as PTEX components.[ PubMed:19536257 PubMed:25043010 PubMed:25043043 ] | ||
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protein-containing complex |__membrane protein complex |__PTEX complex |
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| Is a | membrane protein complex | ||
| Part of | symbiont-containing vacuole membrane | ||
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