FB2025_05 , released December 11, 2025

General Information
Term	phosphatidylinositol 3-kinase complex, class I	ID (Ontology)	GO:0097651 (Gene Ontology)
Definition	A phosphatidylinositol 3-kinase complex that contains a catalytic and a regulatory subunit of a phosphatidylinositol 3-kinase (PI3K) enzyme, plus one or more adaptor proteins. Class I PI3Ks phosphorylate phosphatidylinositol [PI], phosphatidylinositol-4-phosphate [PI(4)P] and phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2], and are divided into subclasses A and B according to the type of adaptor subunit with which they associate. The class I PI3K subfamily of genes comprises members in vertebrates, worm and fly, but none in yeast.
Also Known As	"class I phosphatidylinositol 3-kinase complex" ; "class I PI3K complex"
Comment
Links to External Ontologies
	QuickGO data AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
No relevant records available
Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
No relevant statements available

General Information

Term

phosphatidylinositol 3-kinase complex, class I

ID (Ontology)

GO:0097651 (Gene Ontology)

Definition

A phosphatidylinositol 3-kinase complex that contains a catalytic and a regulatory subunit of a phosphatidylinositol 3-kinase (PI3K) enzyme, plus one or more adaptor proteins. Class I PI3Ks phosphorylate phosphatidylinositol [PI], phosphatidylinositol-4-phosphate [PI(4)P] and phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2], and are divided into subclasses A and B according to the type of adaptor subunit with which they associate. The class I PI3K subfamily of genes comprises members in vertebrates, worm and fly, but none in yeast.

Also Known As

"class I phosphatidylinositol 3-kinase complex" ; "class I PI3K complex"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

No relevant statements available

transferase complex, transferring phosphorus-containing groups__ membrane protein complex________________________________________| phosphatidylinositol 3-kinase complex |__phosphatidylinositol 3-kinase complex, class I 3 rec. |__phosphatidylinositol 3-kinase complex, class IA 3 rec. |__phosphatidylinositol 3-kinase complex, class IB

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	phosphatidylinositol 3-kinase complex
Part of
Synonyms & Secondary IDs
Synonyms
	"class I phosphatidylinositol 3-kinase complex" EXACT "class I PI3K complex" EXACT
Secondary IDs

External Crossreferences & Linkouts

Spanning Tree View Settings

Parents/Children
View Depth

Relationships

Is a

phosphatidylinositol 3-kinase complex

Part of

Synonyms & Secondary IDs

Synonyms

"class I phosphatidylinositol 3-kinase complex" EXACT
"class I PI3K complex" EXACT

Secondary IDs

External Crossreferences & Linkouts