FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
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Term double-strand break repair via classical nonhomologous end joining ID (Ontology) GO:0097680 (Gene Ontology)
Definition An instance of double-strand break repair via nonhomologous end joining that requires a number of factors important for V(D)J recombination, including the KU70/80 heterodimer (KU), XRCC4, ligase IV, and DNA-PKcs in mammals. It does not produce translocations (as opposed to the alternative nonhomologous end joining).[ PubMed:18584027 ]
Also Known As "canonical nonhomologous end joining"
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  double-strand break repair
   |__double-strand break repair via nonhomologous end joining
       |__double-strand break repair via classical nonhomologous end joining
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    "canonical nonhomologous end joining" EXACT
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