FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term membrane protein complex ID (Ontology) GO:0098796 (Gene Ontology)
Definition Any protein complex that is part of a membrane.
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 membrane protein complex (all annotations which use CV term, excluding "NOT" statements)       1
Spanning Tree (Parents/Children)
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cellular_component
 |__protein-containing complex__
cellular anatomical structure   |
 |__membrane____________________|
                                membrane protein complex  730 rec.
                                 |__5-lipoxygenase complex
                                 |__ankyrin-1 complex
                                 |__AP-type membrane coat adaptor complex 18 rec.
                                 |   |__AP-3 adaptor complex 5 rec.
                                 |   |__AP-4 adaptor complex
                                 |   |__AP-5 adaptor complex
                                 |   |__clathrin adaptor complex(+) 13 rec.
                                 |__Asi complex
                                 |__ATG2-ATG18 complex
                                 |__Bam protein complex
                                 |__cargo receptor complex
                                 |   |__low-density lipoprotein receptor complex
                                 |__channel complex
                                 |__chaperone-mediated autophagy translocation complex
                                 |__chloroplast outer membrane translocon
                                 |__chloroplast thylakoid membrane protein complex
                                 |   |__chloroplast photosystem I
                                 |   |__chloroplast photosystem II
                                 |   |__PSII associated light-harvesting complex II, core complex
                                 |   |__PSII associated light-harvesting complex II, peripheral complex(+)
                                 |   |__PSII associated light-harvesting complex II, peripheral complex, LHCIIb subcomplex
                                 |   |__thylakoid light-harvesting complex(+)
                                 |__clathrin complex 3 rec.
                                 |__COPII vesicles tethering complex
                                 |__Derlin-1 retrotranslocation complex 1 rec.
                                 |__Derlin-1-VIMP complex
                                 |__dolichyl-phosphate-mannose-protein mannosyltransferase complex 3 rec.
                                 |   |__dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt2p dimer complex
                                 |   |__dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt3p dimer complex
                                 |   |__dolichyl-phosphate-mannose-protein mannosyltransferase Pmt4p homodimer complex
                                 |   |__dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt2p dimer complex
                                 |   |__dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt3p dimer complex
                                 |__Dsc E3 ubiquitin ligase complex
                                 |__EMC complex 13 rec.
                                 |__endoplasmic reticulum Sec complex 4 rec.
                                 |   |__Sec62/Sec63 complex 3 rec.
                                 |__endosomal scaffold complex
                                 |__ER ubiquitin ligase complex 1 rec.
                                 |   |__CUE1-UBC7 ubiquitin-conjugating enzyme complex
                                 |   |__Doa10p ubiquitin ligase complex
                                 |   |__Hrd1p ubiquitin ligase complex(+) 1 rec.
                                 |__ER-to-endosome phospholipid transfer complex
                                 |__ESCRT I complex 9 rec.
                                 |__ESCRT II complex 4 rec.
                                 |__ESCRT III complex 9 rec.
                                 |__ESCRT IV complex 3 rec.
                                 |__fatty acid elongase complex
                                 |__fumarate reductase complex
                                 |__glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex 6 rec.
                                 |__GPI-anchor transamidase complex 7 rec.
                                 |__H-gal-GP complex
                                 |__HOPS complex 9 rec.
                                 |   |__multivesicular body HOPS complex
                                 |   |__vacuolar HOPS complex(+) 1 rec.
                                 |__inner mitochondrial membrane protein complex 80 rec.
                                 |   |__heterotetrameric polyprenyl diphosphate synthase complex 3 rec.
                                 |   |__i-AAA complex 1 rec.
                                 |   |__INA complex
                                 |   |__m-AAA complex 3 rec.
                                 |   |__MIB complex 1 rec.
                                 |   |__MICOS complex 15 rec.
                                 |   |__mitochondrial complex I intermediate assembly complex 6 rec.
                                 |   |__mitochondrial inner membrane assembly complex
                                 |   |__mitochondrial inner membrane peptidase complex 3 rec.
                                 |   |__mitochondrial prohibitin complex 2 rec.
                                 |   |__mitochondrial pyruvate carrier complex 5 rec.
                                 |   |__mitochondrial respiratory chain complex IV pre-assembly complex
                                 |   |__PAM complex, Tim23 associated import motor 6 rec.
                                 |   |__TIM22 mitochondrial import inner membrane insertion complex 8 rec.
                                 |   |__TIM23 mitochondrial import inner membrane translocase complex(+) 26 rec.
                                 |   |__uniplex complex 8 rec.
                                 |__Ire1 complex
                                 |__IRE1-TRAF2-ASK1 complex
                                 |__lipopolysaccharide receptor complex
                                 |__mannan polymerase complex
                                 |   |__mannan polymerase I complex
                                 |   |__mannan polymerase II complex
                                 |__membrane coat 41 rec.
                                 |   |__AP-type membrane coat adaptor complex 18 rec.
                                 |   |__clathrin coat(+) 20 rec.
                                 |   |__vesicle coat(+) 35 rec.
                                 |__meprin A complex
                                 |__MHC class I peptide loading complex
                                 |   |__TAP complex
                                 |   |__Tapasin-ERp57 complex
                                 |__NADH dehydrogenase complex 59 rec.
                                 |   |__NADH dehydrogenase complex (plastoquinone)
                                 |   |__respiratory chain complex I 59 rec.
                                 |__Nem1-Spo7 phosphatase complex 3 rec.
                                 |__nuclear membrane complex Bqt3-Bqt4
                                 |__nuclear membrane protein complex 5 rec.
                                 |   |__nuclear membrane microtubule tethering complex(+) 3 rec.
                                 |__oligosaccharyltransferase complex 14 rec.
                                 |   |__oligosaccharyltransferase complex A 9 rec.
                                 |   |__oligosaccharyltransferase complex B 8 rec.
                                 |__outer membrane protein complex
                                 |__outer mitochondrial membrane protein complex 18 rec.
                                 |   |__Cdc48p-Npl4p-Vms1p AAA ATPase complex
                                 |   |__ERMES complex
                                 |   |__MIM complex
                                 |   |__mitochondrial outer membrane translocase complex(+) 18 rec.
                                 |__PAS complex 3 rec.
                                 |__PAT complex
                                 |__phosphatidylinositol 3-kinase complex 8 rec.
                                 |   |__phosphatidylinositol 3-kinase complex, class I(+) 3 rec.
                                 |   |__phosphatidylinositol 3-kinase complex, class II
                                 |   |__phosphatidylinositol 3-kinase complex, class III(+) 5 rec.
                                 |__phospholamban complex
                                 |__photosystem
                                 |   |__photosystem I(+)
                                 |   |__photosystem II(+)
                                 |__photosystem I antenna complex
                                 |__photosystem I reaction center
                                 |__photosystem II antenna complex
                                 |__photosystem II oxygen evolving complex
                                 |__photosystem II reaction center
                                 |__phycobilisome
                                 |__plasma membrane protein complex 185 rec.
                                 |   |__alpha1-beta1 integrin-alpha3(VI) complex
                                 |   |__alpha1-beta1 integrin-tissue transglutaminase complex
                                 |   |__alpha1-beta1 integrin-tyrosine-protein phosphatase non-receptor type 2 complex
                                 |   |__alpha2-beta1 integrin-alpha3(VI) complex
                                 |   |__alpha2-beta1 integrin-CD47 complex
                                 |   |__alpha2-beta1 integrin-chondroadherin complex
                                 |   |__alpha3-beta1 integrin-basigin complex
                                 |   |__alpha3-beta1 integrin-CD63 complex
                                 |   |__alpha3-beta1 integrin-CD151 complex
                                 |   |__alpha3-beta1 integrin-thrombospondin complex
                                 |   |__alpha3-beta1 integrin-tissue transglutaminase complex
                                 |   |__alpha4-beta1 integrin-CD47 complex
                                 |   |__alpha4-beta1 integrin-CD53 complex
                                 |   |__alpha4-beta1 integrin-CD63 complex
                                 |   |__alpha4-beta1 integrin-CD81 complex
                                 |   |__alpha4-beta1 integrin-CD82 complex
                                 |   |__alpha4-beta1 integrin-JAM2 complex
                                 |   |__alpha4-beta1 integrin-paxillin complex
                                 |   |__alpha4-beta1 integrin-thrombospondin-1 complex
                                 |   |__alpha4-beta1 integrin-thrombospondin-2 complex
                                 |   |__alpha4-beta4 integrin-EMILIN-1 complex
                                 |   |__alpha5-beta1 integrin-endostatin complex
                                 |   |__alpha5-beta1 integrin-fibronectin-NOV complex
                                 |   |__alpha5-beta1 integrin-fibronectin-tissue transglutaminase complex
                                 |   |__alpha5-beta1 integrin-LPP3 complex
                                 |   |__alpha5-beta1 integrin-osteopontin complex
                                 |   |__alpha5-beta1 integrin-tissue transglutaminase complex
                                 |   |__alpha5-beta5-fibronectin-SFRP2 complex
                                 |   |__alpha6-beta1 integrin-CD151 complex
                                 |   |__alpha6-beta1 integrin-CYR61 complex
                                 |   |__alpha6-beta4 integrin-CD9 complex
                                 |   |__alpha6-beta4 integrin-CD151 complex
                                 |   |__alpha6-beta4 integrin-Fyn complex
                                 |   |__alpha6-beta4 integrin-laminin 5 complex
                                 |   |__alpha6-beta4 integrin-Shc-Grb2 complex
                                 |   |__alpha7-beta1 integrin-CD151 complex
                                 |   |__alpha7-beta1 integrin-focal adhesion kinase complex
                                 |   |__alpha7-beta1 integrin-laminin alpha-2 complex
                                 |   |__alpha7-beta1 integrin-nicotinamide riboside kinase complex
                                 |   |__alpha9-beta1 integrin-ADAM1 complex
                                 |   |__alpha9-beta1 integrin-ADAM2 complex
                                 |   |__alpha9-beta1 integrin-ADAM3 complex
                                 |   |__alpha9-beta1 integrin-ADAM8 complex
                                 |   |__alpha9-beta1 integrin-ADAM9 complex
                                 |   |__alpha9-beta1 integrin-ADAM12 complex
                                 |   |__alpha9-beta1 integrin-ADAM15 complex
                                 |   |__alpha9-beta1 integrin-osteopontin complex
                                 |   |__alpha9-beta1 integrin-tenascin complex
                                 |   |__alpha9-beta1 integrin-thrombospondin-1 complex
                                 |   |__alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex
                                 |   |__alpha9-beta1 integrin-VEGF-A complex
                                 |   |__alpha9-beta1 integrin-VEGF-C complex
                                 |   |__alpha9-beta1 integrin-VEGF-D complex
                                 |   |__alpha11-beta1 integrin-collagen type I complex
                                 |   |__alphaE-beta7 integrin-E-cadherin complex
                                 |   |__alphaIIb-beta3 integrin-CD9 complex
                                 |   |__alphaIIb-beta3 integrin-CD9-CD47-platelet glycoprotein Ib complex
                                 |   |__alphaIIb-beta3 integrin-CD47-FAK complex
                                 |   |__alphaIIb-beta3 integrin-CD47-Src complex
                                 |   |__alphaIIb-beta3 integrin-CIB complex
                                 |   |__alphaIIb-beta3 integrin-fibronectin-tissue transglutaminase complex
                                 |   |__alphaIIb-beta3 integrin-ICAM-4 complex
                                 |   |__alphaIIb-beta3 integrin-talin complex
                                 |   |__alphaM-beta2 integrin-CD63 complex
                                 |   |__alphaPDGFR-PLC-gamma-1-PI3K-SHP-2 complex
                                 |   |__alphaPDGFR-SHP-2 complex
                                 |   |__alphav-beta1 integrin-osteopontin complex
                                 |   |__alphav-beta3 integrin-ADAM15 complex
                                 |   |__alphav-beta3 integrin-ADAM23 complex
                                 |   |__alphav-beta3 integrin-CD47 complex
                                 |   |__alphaV-beta3 integrin-CD47-FCER2 complex
                                 |   |__alphaV-beta3 integrin-CD98 complex
                                 |   |__alphav-beta3 integrin-collagen alpha3(VI) complex
                                 |   |__alphaV-beta3 integrin-EGFR complex
                                 |   |__alphaV-beta3 integrin-gelsolin complex
                                 |   |__alphav-beta3 integrin-HMGB1 complex
                                 |   |__alphav-beta3 integrin-IGF-1-IGF1R complex
                                 |   |__alphaV-beta3 integrin-laminin alpha-4 complex
                                 |   |__alphaV-beta3 integrin-LPP3 complex
                                 |   |__alphaV-beta3 integrin-NOV complex
                                 |   |__alphav-beta3 integrin-osteopontin complex
                                 |   |__alphaV-beta3 integrin-paxillin-Pyk2 complex
                                 |   |__alphav-beta3 integrin-PKCalpha complex
                                 |   |__alphav-beta3 integrin-thrombospondin complex
                                 |   |__alphaV-beta3 integrin-tissue transglutaminase complex
                                 |   |__alphaV-beta3 integrin-tumstatin complex
                                 |   |__alphav-beta3 integrin-vitronectin complex
                                 |   |__alphav-beta5 integrin-osteopontin complex
                                 |   |__alphav-beta5 integrin-vitronectin complex
                                 |   |__alphaV-beta6 integrin-osteopontin complex
                                 |   |__alphaV-beta6 integrin-TGFbeta-3 complex
                                 |   |__alphaV-beta8 integrin-MMP14-TGFbeta-1 complex
                                 |   |__alphaX-beta2 integrin-ICAM-4 complex
                                 |   |__amino acid transport complex
                                 |   |__AP-2 adaptor complex 7 rec.
                                 |   |__ATP-binding cassette (ABC) transporter complex(+) 6 rec.
                                 |   |__auxin efflux carrier complex
                                 |   |__bacterial-type flagellum stator complex
                                 |   |__catenin complex 8 rec.
                                 |   |__caveolar macromolecular signaling complex
                                 |   |__CD19-Vav-PIK3R1 complex
                                 |   |__CFTR-NHERF-ezrin complex
                                 |   |__ciliary necklace
                                 |   |__clathrin coat of coated pit(+) 10 rec.
                                 |   |__connexin complex
                                 |   |__contractile vacuole pore
                                 |   |__Cus cation efflux complex
                                 |   |__D-amino-acid dehydrogenase complex
                                 |   |__death-inducing signaling complex(+) 1 rec.
                                 |   |__Delta1 complex
                                 |   |__dystrobrevin complex
                                 |   |__dystroglycan complex(+) 5 rec.
                                 |   |__dystrophin-associated glycoprotein complex(+) 13 rec.
                                 |   |__EFF-1 complex
                                 |   |__EGFR-Grb2-Sos complex
                                 |   |__EGFR-Shc-Grb2-Sos complex
                                 |   |__EmrE multidrug transporter complex
                                 |   |__Fc receptor complex(+)
                                 |   |__fibronectin-tissue transglutaminase complex
                                 |   |__flotillin complex 3 rec.
                                 |   |__gamma-secretase complex 5 rec.
                                 |   |__gamma-secretase-Delta1 complex
                                 |   |__glycine-gated chloride channel complex
                                 |   |__Grb2-EGFR complex
                                 |   |__Grb2-Shc complex
                                 |   |__Grb2-SHP-2 complex
                                 |   |__Grb2-Sos complex
                                 |   |__heterotrimeric G-protein complex 18 rec.
                                 |   |__high-affinity iron permease complex
                                 |   |__histamine-gated chloride channel complex 3 rec.
                                 |   |__inaD signaling complex 10 rec.
                                 |   |__inhibin-betaglycan-ActRII complex
                                 |   |__interleukin-12-interleukin-12 receptor complex
                                 |   |__interleukin4-interleukin-4 receptor complex
                                 |   |__inward rectifying potassium channel
                                 |   |__low-density lipoprotein receptor complex
                                 |   |__MalFGK2 complex
                                 |   |__MdtBC Complex
                                 |   |__membrane attack complex
                                 |   |__MHC protein complex(+)
                                 |   |__MPP7-DLG1-LIN7 complex
                                 |   |__NADPH oxidase complex 2 rec.
                                 |   |__NarGHI complex
                                 |   |__Ost-alpha/Ost-beta complex
                                 |   |__plasma membrane proton-transporting V-type ATPase complex(+) 14 rec.
                                 |   |__plasma membrane proton-transporting V-type ATPase, V0 domain
                                 |   |__plasma membrane proton-transporting V-type ATPase, V1 domain
                                 |   |__plasma membrane signaling receptor complex(+) 45 rec.
                                 |   |__plasma membrane-derived photosystem I
                                 |   |__plasma membrane-derived thylakoid photosystem II
                                 |   |__plasma membrane-derived thylakoid ribulose bisphosphate carboxylase complex
                                 |   |__platelet-derived growth factor receptor-ligand complex
                                 |   |__potassium:proton exchanging ATPase complex
                                 |   |__protocadherin-alpha-protocadherin-gamma complex(+)
                                 |   |__sarcoglycan complex 4 rec.
                                 |   |__SC5b-7 complex
                                 |   |__Shc-EGFR complex
                                 |   |__Shc-Grb2-Sos complex
                                 |   |__sodium:potassium-exchanging ATPase complex 7 rec.
                                 |   |__subapical complex 11 rec.
                                 |   |__sucrase-isomaltase complex
                                 |   |__syntrophin complex 3 rec.
                                 |   |__TAT protein transport complex
                                 |   |__transmembrane collagen trimer(+)
                                 |   |__voltage-gated calcium channel complex(+) 11 rec.
                                 |   |__voltage-gated potassium channel complex(+) 15 rec.
                                 |   |__voltage-gated sodium channel complex 3 rec.
                                 |   |__Wnt-Frizzled-LRP5/6 complex 2 rec.
                                 |__pore complex 2 rec.
                                 |   |__glomerular endothelium fenestra
                                 |   |__membrane attack complex
                                 |   |__mitochondrial permeability transition pore complex 2 rec.
                                 |__pre-B cell receptor complex
                                 |__protein C inhibitor-acrosin complex
                                 |__proton-transporting two-sector ATPase complex 72 rec.
                                 |   |__archaeal proton-transporting A-type ATPase complex
                                 |   |__proton-transporting ATP synthase complex 31 rec.
                                 |   |__proton-transporting two-sector ATPase complex, catalytic domain 14 rec.
                                 |   |__proton-transporting two-sector ATPase complex, proton-transporting domain 20 rec.
                                 |   |__proton-transporting V-type ATPase complex(+) 41 rec.
                                 |__proton-transporting two-sector ATPase complex, catalytic domain 14 rec.
                                 |   |__proton-transporting V-type ATPase, V1 domain(+) 14 rec.
                                 |__proton-transporting two-sector ATPase complex, proton-transporting domain 20 rec.
                                 |   |__proton-transporting V-type ATPase, V0 domain(+) 19 rec.
                                 |__PTEX complex
                                 |__Ragulator complex 6 rec.
                                 |__respiratory chain complex II (succinate dehydrogenase) 10 rec.
                                 |__retromer complex 9 rec.
                                 |   |__retromer, cargo-selective complex 4 rec.
                                 |   |__retromer, tubulation complex 2 rec.
                                 |__retromer, cargo-selective complex 4 rec.
                                 |__retromer, tubulation complex 2 rec.
                                 |__Sec62/Sec63 complex 3 rec.
                                 |__signal peptidase complex 5 rec.
                                 |__signal recognition particle receptor complex 3 rec.
                                 |__SNARE complex 36 rec.
                                 |   |__cellubrevin-VAMP4-endobrevin-syntaxin-6 complex
                                 |   |__cellubrevin-VAMP4-syntaxin-16 complex
                                 |   |__endobrevin-SNAP-25-syntaxin-1a complex
                                 |   |__endobrevin-SNAP-25-syntaxin-2 complex
                                 |   |__endobrevin-synaptobrevin 2-alpha-SNAP-NSF-syntaxin-4 complex
                                 |   |__platelet SNARE complex
                                 |   |__synaptobrevin 2-SNAP-25-syntaxin-1a complex
                                 |   |__synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex
                                 |   |__synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex
                                 |   |__synaptobrevin 2-SNAP-25-syntaxin-2 complex
                                 |   |__synaptobrevin 2-SNAP-25-syntaxin-3 complex
                                 |   |__synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex
                                 |   |__synaptobrevin 2-SNAP-25-syntaxin-4 complex
                                 |   |__synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Rab3a complex
                                 |   |__synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Rab3a-complexin II complex
                                 |   |__synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Unc13 complex
                                 |   |__syntaxin-6-syntaxin-16-Vti1a complex
                                 |   |__VAMP4-syntaxin-6-syntaxin-16-Vti1a complex
                                 |__sodium ion-transporting two-sector ATPase complex
                                 |   |__sodium ion-transporting F-type ATPase complex
                                 |   |__sodium ion-transporting V-type ATPase complex
                                 |__SREBP-SCAP complex 2 rec.
                                 |__SREBP-SCAP-Insig complex
                                 |__starch utilization system complex
                                 |__STING complex
                                 |__TAP complex
                                 |__Tapasin-ERp57 complex
                                 |__Tic complex
                                 |__Toc complex
                                 |__translocon complex 9 rec.
                                 |   |__Sec61 translocon complex 8 rec.
                                 |   |__Ssh1 translocon complex 3 rec.
                                 |__transmembrane transporter complex 323 rec.
                                 |   |__ammonium transmembrane transporter complex
                                 |   |__ATPase dependent transmembrane transport complex(+) 54 rec.
                                 |   |__calcium:proton antiporter complex
                                 |   |__copper ion transmembrane transporter complex(+)
                                 |   |__curli secretion complex
                                 |   |__cytochrome o ubiquinol oxidase complex
                                 |   |__efflux pump complex
                                 |   |__EmrE multidrug transporter complex
                                 |   |__high-affinity iron exporter complex
                                 |   |__high-affinity iron permease complex
                                 |   |__macrolide transmembrane transporter complex(+)
                                 |   |__MdtBC Complex
                                 |   |__methionine-importing complex(+)
                                 |   |__mitochondrial pyruvate carrier complex 5 rec.
                                 |   |__monoatomic ion channel complex(+) 158 rec.
                                 |   |__potassium:proton antiporter complex
                                 |   |__protein-N(PI)-phosphohistidine-sugar phosphotransferase complex
                                 |   |__respiratory chain complex I 59 rec.
                                 |   |__respiratory chain complex III 18 rec.
                                 |   |__respiratory chain complex IV 27 rec.
                                 |   |__S100A9 complex
                                 |   |__silver ion transmembrane transporter complex(+)
                                 |__UDP-N-acetylglucosamine transferase complex 4 rec.
                                 |__vacuolar transporter chaperone complex
                                 |__VCP-NPL4-UFD1 AAA ATPase complex 3 rec.
                                 |__Vps55/Vps68 complex
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