FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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Term symbiont entry into host cell via permeabilization of endosomal membrane ID (Ontology) GO:0099006 (Gene Ontology)
Definition The entry of a symbiont into a host cell, following endocytosis, via permeabilization of the endosomal membrane by membrane penetration protein(s) of the symbiont. This process mediates the entry of some non-enveloped virus into eukaryotic cells. In some cases, viral membrane-penetration protein requires to be activated to display its membrane penetrating activity. Activation can be due to receptor binding or the acidic pH of the endosomal lumen.[ PubMed:15329727 PubMed:25055856 ]
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symbiont entry into host cell____________________
symbiont-mediated perturbation of host membrane__|
                                                 symbiont entry into host cell via permeabilization of host membrane
                                                  |__symbiont entry into host cell via permeabilization of endosomal membrane
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  • "viral entry via permeabilization of endosomal membrane" NARROW
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