FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term vesicle tethering ID (Ontology) GO:0099022 (Gene Ontology)
Definition The initial, indirect interaction between a vesicle membrane and a membrane to which it is targeted for fusion. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to interaction between factors involved in fusion.[ PubMed:27243008 ]
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  cellular component organization or biogenesis
   |__cellular component organization
       |__vesicle tethering  11 rec.
           |__vesicle tethering involved in exocytosis 6 rec.
           |   |__contractile vacuole tethering involved in discharge
           |   |__exocytic insertion of neurotransmitter receptor to plasma membrane
           |   |__synaptic vesicle tethering involved in synaptic vesicle exocytosis 3 rec.
           |__vesicle tethering to endoplasmic reticulum 1 rec.
           |__vesicle tethering to Golgi 4 rec.
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Is a cellular component organization
Part of vesicle targeting
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