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| Term | B-WICH complex | ID (Ontology) | GO:0110016 (Gene Ontology) |
| Definition | A chromatin remodeling complex that positively regulates histone H3 acetylation, in particular H3K9, by recruiting histone acetyltransferases to rDNA gene regions. Located in the nucleolus where it assembles on RNA Polymerase I (Pol I) and possibly on RNA Polymerase III (Pol III) promoter and coding regions during early G1 phase and activates the post-initiation phases of Pol I transcription. May also activate RNA Polymerase II (Pol II) gene transcription. In mammals, B-WICH contains the WICH complex core of BAZ1B and SMARCA5, additional protein subunits and possibly rRNAs. Although it contains several catalytic subunits it is not clear which functions are carried out by the complex itself.[ PubMed:16603771 PubMed:21559432 PubMed:23555303 PubMed:26044184 ] | ||
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chromatin |__SWI/SNF superfamily-type complex__ nuclear lumen | |__nucleolus_________________________| intracellular membraneless organelle | |__nucleolus_________________________| nuclear protein-containing complex | |__SWI/SNF superfamily-type complex__| ATPase complex | |__SWI/SNF superfamily-type complex__| B-WICH complex |
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| Is a | SWI/SNF superfamily-type complex | ||
| Part of | nucleolus | ||
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