FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term reelin complex ID (Ontology) GO:0110157 (Gene Ontology)
Definition An extracellular complex that binds lipoprotein receptors VLDLR and APOER2, cadherin-related neuronal receptors (CNRs) or alpha3beta1 integrin and induces various downstream, reelin-dependent, phosphorylation cascades. It ultimately affects polarization, differentiation, neuronal migration and layer formation in the embryonic brain and neuron growth, maturation, and synaptic activity in the postnatal and adult brain.[ PubMed:21844191 PubMed:28887403 ]
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cellular_component
 |__protein-containing complex__
extracellular region            |
 |__extracellular space_________|
cellular anatomical structure   |
 |__extracellular space_________|
                                reelin complex
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Is a protein-containing complex
Part of extracellular space
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