General Information
Term	Sm-like protein family complex	ID (Ontology)	GO:0120114 (Gene Ontology)
Definition	A protein complex containing members of the Like-Sm family of proteins, which includes both the Sm proteins and the Lsm proteins, and which generally form hexameric or heptameric ring structures which bind to RNA. While some of these ring complexes may form independently of RNA, many only form in association with their target RNA. In addition to Lsm-family proteins, many of these complexes contain additional protein members. Members of this family of complexes include the snRNPs which comprise the majority of the spliceosome. Others are involved in the 5' to 3' degradation pathways of mRNAs in the cytoplasm and of unspliced transcripts in the nucleus, as well as other diverse roles.[ PubMed:19121818 PubMed:27627834 ]
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General Information

Term

Sm-like protein family complex

ID (Ontology)

GO:0120114 (Gene Ontology)

Definition

A protein complex containing members of the Like-Sm family of proteins, which includes both the Sm proteins and the Lsm proteins, and which generally form hexameric or heptameric ring structures which bind to RNA. While some of these ring complexes may form independently of RNA, many only form in association with their target RNA. In addition to Lsm-family proteins, many of these complexes contain additional protein members. Members of this family of complexes include the snRNPs which comprise the majority of the spliceosome. Others are involved in the 5' to 3' degradation pathways of mRNAs in the cytoplasm and of unspliced transcripts in the nucleus, as well as other diverse roles.[ PubMed:19121818 PubMed:27627834 ]

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

No relevant statements available

  cellular_component
   |__protein-containing complex
       |__Sm-like protein family complex  124 rec.
           |__Lsm1-7-Pat1 complex 5 rec.
           |__Lsm2-8 complex
           |__pICln-Sm protein complex 5 rec.
           |__small nuclear ribonucleoprotein complex 109 rec.
           |   |__7SK snRNP 4 rec.
           |   |__spliceosomal snRNP complex(+) 91 rec.
           |   |__U7 snRNP 3 rec.
           |__SMN complex 12 rec.
           |__SMN-Gemin2 complex 2 rec.
           |__SMN-Sm protein complex 16 rec.
               |__Lsm-containing SMN-Sm protein complex 1 rec.
               |__SmD-containing SMN-Sm protein complex 2 rec.
               |__SMN complex 12 rec.

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