Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
No relevant statements available
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| Term | ubiquitin activating enzyme complex | ID (Ontology) | GO:0120123 (Gene Ontology) |
| Definition | A protein complex responsible for the catalysis of the reaction: E1 + ubiquitin + ATP--> E1-ubiquitin + AMP + PPi, where the E1-ubiquitin linkage is a thioester bond between the C-terminal glycine of Ub and a sulfhydryl side group of an E1 cysteine residue. This is the first step in a cascade of reactions in which ubiquitin is ultimately added to a protein substrate.[ PubMed:9545234 ] | ||
| Also Known As | "E1 complex" | ||
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protein-containing complex |__intracellular protein-containing complex__ |__catalytic complex_________________________| ubiquitin activating enzyme complex |
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intracellular protein-containing complex catalytic complex |
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