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General Information
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| Term |
phospholipase C-activating N-formyl peptide-activated signaling pathway |
ID (Ontology) |
GO:0140307 (Gene Ontology) |
| Definition |
A phospholipase C-activating G protein-coupled receptor signaling pathway initiated by an N-formyl peptide binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. chemotaxis. N-formyl peptides include N-formylmethionyl-leucyl-phenylalanine (fMLF, fMLP or N-formyl-met-leu-phe), an N-formylated tripeptide sometimes simply referred to as chemotactic peptide. fMLF is a potent polymorphonuclear leukocyte (PMN) chemotactic factor and is also a macrophage activator.[ PubMed:10466071 PubMed:22728827 PubMed:23994464 ] |
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Links to External Ontologies
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QuickGO data AmiGO data
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Annotations
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Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
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No relevant records available
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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No relevant statements available
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Relationships
