FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term Frizzled Nuclear Import pathway ID (Ontology) GO:0140709 (Gene Ontology)
Definition A type of non-canonical Wnt signaling in which Wnt binding to its receptor on the surface a the target cell results in internalization and cleavage of the frizzled receptor to yield a C-terminal fragment that is imported into the nucleus. The frizzled C-terminal fragment is incorporated into large ribonucleoprotein particles and stimulates their egress via nuclear budding.[ PubMed:22510459 PubMed:22579286 ]
Also Known As "Frizzled Nuclear Import Wnt Pathway"
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       1
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Relevant FlyBase reports
 Genes
 Frizzled Nuclear Import pathway (all annotations which use CV term, excluding "NOT" statements)       1
     involved_in | Frizzled Nuclear Import pathway       1
Spanning Tree (Parents/Children)
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  Wnt signaling pathway
   |__non-canonical Wnt signaling pathway
       |__Frizzled Nuclear Import pathway  1 rec.
           |__regulation of Frizzled Nuclear Import pathway
               |__negative regulation of Frizzled Nuclear Import pathway
               |__positive regulation of Frizzled Nuclear Import pathway
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Is a non-canonical Wnt signaling pathway
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Synonyms
  • "FNI" BROAD
    "Frizzled Nuclear Import Wnt Pathway" EXACT
Secondary IDs
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