FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term facultative heterochromatin formation ID (Ontology) GO:0140718 (Gene Ontology)
Definition The compaction of chromatin into a conformation that is refractory to transcription but that can be converted to euchromatin and allow transcription in specific contexts. These can be temporal (e.g., developmental states or specific cell-cycle stages), spatial (e.g., nuclear localization changes from the center to the periphery or vice versa due to exogenous factors/signals), or parental/heritable (e.g., monoallelic gene expression). In metazoa, this involves the methylation of histone H3K27.[ PubMed:17936700 ]
Also Known As "facultative heterochromatin assembly" ; "fHC assembly"
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       6
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 facultative heterochromatin formation (all annotations which use CV term, excluding "NOT" statements)       6
     involved_in | facultative heterochromatin formation       6
Spanning Tree (Parents/Children)
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cellular component assembly_________________________
negative regulation of gene expression, epigenetic__|
heterochromatin organization________________________|
                                                    heterochromatin formation
                                                     |__facultative heterochromatin formation  8 rec.
                                                         |__rDNA heterochromatin formation 2 rec.
                                                         |   |__regulation of rDNA heterochromatin formation(+)
                                                         |__siRNA-independent facultative heterochromatin formation
                                                         |   |__regulation of siRNA-independent facultative heterochromatin formation
                                                         |__siRNA-mediated facultative heterochromatin formation
                                                             |__regulation of siRNA-mediated facultative heterochromatin formation
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Is a heterochromatin formation
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Synonyms
  • "facultative heterochromatin assembly" EXACT
    "fHC assembly" EXACT
Secondary IDs
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