FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term self-resistance to endogenously produced metabolite ID (Ontology) GO:0140729 (Gene Ontology)
Definition A process that reduces or removes the toxicity of an endogenously produced substance. Mechanisms of resistance to endogenously produced compounds include modification the compound, export, sequestration, or mutations in the target enzyme.[ PubMed:21923907 PubMed:29763292 ]
Also Known As "prevention of self-toxicity" ; "self-resistance to bioactive secondary metabolite" ; "self-resistance to endogenously produced compound" (for all, see Synonyms field below)
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biological_process___________
response to toxic substance__|
                             detoxification
                              |__self-resistance to endogenously produced metabolite
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Synonyms
  • "prevention of self-toxicity" EXACT
    "self-resistance to bioactive secondary metabolite" EXACT
    "self-resistance to endogenously produced compound" EXACT
    "self-resistance to endogenously produced toxin" EXACT
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