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| Term | chromosomal 5-methylcytosine DNA demethylation, oxidative deamination pathway | ID (Ontology) | GO:0141168 (Gene Ontology) |
| Definition | An epigenetic cytosine DNA demethylation pathway that includes a deamination step to produce either a thymine (T), or a 5-hydroxymethyluracil (5hmU), if the 5meC had first been converted to 5hmC. A DNA glycosylase (e. g. TDG) recognizes the T mispaired with a G or the 5hmC and excises the modified base to initiate its replacement with unmethylated cytosine through base excision repair.[ PubMed:21862972 PubMed:29875631 PubMed:36478523 ] | ||
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DNA metabolic process |__DNA repair______________________________________________ |__chromosomal 5-methylcytosine DNA demethylation pathway__| DNA damage response | |__DNA repair______________________________________________| chromosomal 5-methylcytosine DNA demethylation, oxidative deamination pathway |
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DNA repair chromosomal 5-methylcytosine DNA demethylation pathway |
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