FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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Term chromosomal 5-methylcytosine DNA demethylation, direct 5-methylcytosine excision pathway ID (Ontology) GO:0141169 (Gene Ontology)
Definition An epigenetic cytosine DNA demethylation pathway that involves a DNA glycosylase that directly excises 5-methylcytosine (5-meC) to initiate its replacement with unmethylated cytosine through base excision repair. This pathway is known to occur in plants. In addition to CG sites, plants also methylate cytosines within CHH and CNG sequences.[ PubMed:21862972 PubMed:31546611 PubMed:36478523 ]
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  DNA metabolic process
   |__chromosomal 5-methylcytosine DNA demethylation pathway
       |__chromosomal 5-methylcytosine DNA demethylation, direct 5-methylcytosine excision pathway
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Is a chromosomal 5-methylcytosine DNA demethylation pathway
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Synonyms
  • "epigenetic 5-methylcytosine DNA demethylation, direct 5-methylcytosine excision pathway" RELATED
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