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| Term | Cyc8(Ssn6)-Tup1 general repressor complex | ID (Ontology) | GO:0160051 (Gene Ontology) |
| Definition | A corepressor complex containing the WD-repeat protein Tup1p (S. cerevisiae) and Tup11/Tup12 (fission yeast) and the TPR repeat protein Cyc8p (S. cerevisiae) ssn6 (fission yeast) that is recruited to target genes by DNA-bound repressor proteins preferentially at regions where histones are deacetylated by the Clr6 class I HDAC, and recruits the SWI/SNF and SAGA complexes to promoters.[ PubMed:10871883 PubMed:17101775 PubMed:22156212 ] | ||
| Also Known As | "Tup11/Tup12 repressor complex" | ||
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transcription repressor complex_____ nuclear protein-containing complex__| RNA polymerase II transcription repressor complex |__Cyc8(Ssn6)-Tup1 general repressor complex |
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| Is a | RNA polymerase II transcription repressor complex | ||
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