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| Term | multi-pass translocon complex | ID (Ontology) | GO:0160064 (Gene Ontology) |
| Definition | A protein complex that mediates the insertion of multi-pass transmembrane proteins into endoplasmic reticulum (ER) membrane. Substrates enter via the lateral gate of the Sec61 translocon. The complex comprises the GEL subcomplex (composed of RAB5IF/OPTI and TMCO1), the BOS subcomplex (composed of NCLN/Nicalin, NOMO and TMEM147) and the PAT subcomplex (composed of WDR83OS/Asterix and CCDC47).[ PubMed:36261522 PubMed:36261528 ] | ||
| Also Known As | "MPT complex" | ||
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protein-containing complex |__ER membrane insertion complex |__multi-pass translocon complex |
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| Is a | ER membrane insertion complex | ||
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