FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term oxoadipate dehydrogenase complex ID (Ontology) GO:0160167 (Gene Ontology)
Definition A multi-enzyme complex that catalyzes the oxidative decarboxylation of 2-oxoadipate to glutaryl-CoA, thereby acting in the final step of lysine and tryptophan catabolism in mitochondria. The complex comprises multiple copies of three enzymes referred to as E1, E2 and E3: 2-oxoadipate dehydrogenase (E1), dihydrolipoamide S-succinyltransferase (E2) and dihydrolipoamide dehydrogenase (E3).[ PubMed:29191460 PubMed:32695416 ]
Also Known As "OADHC"
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       2
Genes (FBgn)  GO_CELLULAR_COMPONENT       3
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 Gene Groups Genes
 oxoadipate dehydrogenase complex (all annotations which use CV term, excluding "NOT" statements)       2      3
     part_of | oxoadipate dehydrogenase complex       --       3
Spanning Tree (Parents/Children)
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  oxidoreductase complex
   |__alpha-ketoacid dehydrogenase complex
       |__oxoadipate dehydrogenase complex  5 rec.
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Is a alpha-ketoacid dehydrogenase complex
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Synonyms
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