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| Term | transcription pausing by RNA polymerase II | ID (Ontology) | GO:0160239 (Gene Ontology) |
| Definition | A transcription halt following transcription initiation but prior to elongation, during which RNA polymerase II pauses approximately 20-60 nucleotides downstream of the transcriptional start site before proceeding into productive elongation. Transcription pausing starts following phosphorylation of the C-terminal domain (CTD) of RNA polymerase II subunit POLR2A at Ser-5 and stops following phosphorylation of POLR2A by the P-TEFb complex.[ PubMed:33271312 PubMed:35816930 ] | ||
| Also Known As | "promoter proximal pausing by RNA polymerase II" | ||
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DNA-templated transcription |__transcription by RNA polymerase II__ RNA metabolic process | |__RNA biosynthetic process____________| nucleic acid biosynthetic process | |__RNA biosynthetic process____________| transcription pausing by RNA polymerase II |
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| Is a | RNA biosynthetic process | ||
| Part of | transcription by RNA polymerase II | ||
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