FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term Knl1/Spc105 complex ID (Ontology) GO:0180019 (Gene Ontology)
Definition A kinetochore subcomplex that binds to centromeric chromatin and forms part of the outer kinetochore. It helps to recruit outer kinetochore subunits that will bind to microtubules. In humans and yeast respectively, it consists of KNL1/Spc105p and ZWINT/Kre28p.[ PubMed:27881301 ]
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kinetochore
 |__outer kinetochore___________
cellular_component              |
 |__protein-containing complex__|
protein-containing complex      |
 |__outer kinetochore___________|
                                Knl1/Spc105 complex
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Is a protein-containing complex
Part of outer kinetochore
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