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General Information
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| Term |
RQC-trigger complex |
ID (Ontology) |
GO:0180022 (Gene Ontology) |
| Definition |
A ribosome disassembly complex which dissociates stalled ribsome subunits as part of the ribosome quality control pathway. RQT complex is composed of a RNA helicase-family protein yeast Rqt2 (human ASCC3), a ubiquitin-binding protein yeast Rqt3, (human ASCC2), and Rqt4 (human TRIP4). The human complex has an additional component protein ASCC1 and can act as a transcriptional coactivator by interacting with transcription factors such as NF-kappa B.[ PubMed:12077347 PubMed:28757607 PubMed:32099016 ] |
| Also Known As |
"activating signal cointegrator 1 complex" ; "ASC-1 complex" ; "RQT complex" |
| Comment |
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Links to External Ontologies
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QuickGO data AmiGO data
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Annotations
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Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
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| Data Class | Field | Records |
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| Genes (FBgn) | GO_CELLULAR_COMPONENT | 1 |
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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| Full annotation statements | Relevant FlyBase reports |
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| Genes |
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RQC-trigger complex (all annotations which use CV term, excluding "NOT" statements) | 1 | part_of | RQC-trigger complex | 1 |
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Relationships
