FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term negative regulation of IRE1-mediated unfolded protein response ID (Ontology) GO:1903895 (Gene Ontology)
Definition Any process that stops, prevents or reduces the frequency, rate or extent of the IRE1-mediated unfolded protein response.[ PubMed:22013210 ]
Also Known As "down regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling" ; "down regulation of IRE1 branch of UPR" ; "down regulation of IRE1-mediated unfolded protein response" (for all, see Synonyms field below)
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       1
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 Genes
 negative regulation of IRE1-mediated unfolded protein response (all annotations which use CV term, excluding "NOT" statements)       1
     involved_in | negative regulation of IRE1-mediated unfolded protein response       1
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regulation of endoplasmic reticulum unfolded protein response
 |__negative regulation of endoplasmic reticulum unfolded protein response__
 |__regulation of IRE1-mediated unfolded protein response___________________|
negative regulation of intracellular signal transduction                    |
 |__negative regulation of endoplasmic reticulum unfolded protein response__|
negative regulation of response to endoplasmic reticulum stress             |
 |__negative regulation of endoplasmic reticulum unfolded protein response__|
                                                                            negative regulation of IRE1-mediated unfolded protein response  1 rec.
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Is a negative regulation of endoplasmic reticulum unfolded protein response
regulation of IRE1-mediated unfolded protein response
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Synonyms
  • "down regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling" EXACT
    "down regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction" RELATED
    "down regulation of IRE1 branch of UPR" EXACT
    "down regulation of IRE1 signaling in response to endoplasmic reticulum stress" RELATED
    "down regulation of IRE1-mediated unfolded protein response" EXACT
    "down regulation of IRE1alpha unfolded protein response" NARROW
    "down regulation of IRE1p unfolded protein response" NARROW
    "down regulation of UPR signaling by IRE1 stress sensor" EXACT
    "down-regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling" EXACT
    "down-regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction" RELATED
    "down-regulation of IRE1 branch of UPR" EXACT
    "down-regulation of IRE1 signaling in response to endoplasmic reticulum stress" RELATED
    "down-regulation of IRE1-mediated unfolded protein response" EXACT
    "down-regulation of IRE1alpha unfolded protein response" NARROW
    "down-regulation of IRE1p unfolded protein response" NARROW
    "down-regulation of UPR signaling by IRE1 stress sensor" EXACT
    "downregulation of endoplasmic reticulum unfolded protein response; IRE1 signaling" EXACT
    "downregulation of inositol-requiring transmembrane kinase/endonuclease signal transduction" RELATED
    "downregulation of IRE1 branch of UPR" EXACT
    "downregulation of IRE1 signaling in response to endoplasmic reticulum stress" RELATED
    "downregulation of IRE1-mediated unfolded protein response" EXACT
    "downregulation of IRE1alpha unfolded protein response" NARROW
    "downregulation of IRE1p unfolded protein response" NARROW
    "downregulation of UPR signaling by IRE1 stress sensor" EXACT
    "inhibition of endoplasmic reticulum unfolded protein response; IRE1 signaling" NARROW
    "inhibition of inositol-requiring transmembrane kinase/endonuclease signal transduction" RELATED
    "inhibition of IRE1 branch of UPR" NARROW
    "inhibition of IRE1 signaling in response to endoplasmic reticulum stress" RELATED
    "inhibition of IRE1-mediated unfolded protein response" NARROW
    "inhibition of IRE1alpha unfolded protein response" NARROW
    "inhibition of IRE1p unfolded protein response" NARROW
    "inhibition of UPR signaling by IRE1 stress sensor" NARROW
    "negative regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling" EXACT
    "negative regulation of ERN1-mediated unfolded protein response" RELATED
    "negative regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction" RELATED
    "negative regulation of IRE1 branch of UPR" EXACT
    "negative regulation of IRE1 signaling in response to endoplasmic reticulum stress" RELATED
    "negative regulation of IRE1alpha unfolded protein response" NARROW
    "negative regulation of IRE1p unfolded protein response" NARROW
    "negative regulation of UPR signaling by IRE1 stress sensor" EXACT
Secondary IDs
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