FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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Term negative regulation of PERK-mediated unfolded protein response ID (Ontology) GO:1903898 (Gene Ontology)
Definition Any process that stops, prevents or reduces the frequency, rate or extent of the PERK-mediated unfolded protein response.[ PubMed:22013210 ]
Also Known As "down regulation of endoplasmic reticulum unfolded protein response; PERK signaling" ; "down regulation of PERK branch of UPR" ; "down regulation of PERK-mediated unfolded protein response" (for all, see Synonyms field below)
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PERK-mediated unfolded protein response
 |__regulation of PERK-mediated unfolded protein response___________________
regulation of endoplasmic reticulum unfolded protein response               |
 |__negative regulation of endoplasmic reticulum unfolded protein response__|
 |__regulation of PERK-mediated unfolded protein response___________________|
negative regulation of intracellular signal transduction                    |
 |__negative regulation of endoplasmic reticulum unfolded protein response__|
negative regulation of response to endoplasmic reticulum stress             |
 |__negative regulation of endoplasmic reticulum unfolded protein response__|
                                                                            negative regulation of PERK-mediated unfolded protein response
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Is a negative regulation of endoplasmic reticulum unfolded protein response
regulation of PERK-mediated unfolded protein response
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Synonyms
  • "down regulation of endoplasmic reticulum unfolded protein response; PERK signaling" EXACT
    "down regulation of PERK branch of UPR" EXACT
    "down regulation of PERK signaling in response to endoplasmic reticulum stress" RELATED
    "down regulation of PERK-mediated unfolded protein response" EXACT
    "down regulation of PKR-like ER kinase signal transduction" EXACT
    "down regulation of UPR signaling by PERK stress sensor" EXACT
    "down-regulation of endoplasmic reticulum unfolded protein response; PERK signaling" EXACT
    "down-regulation of PERK branch of UPR" EXACT
    "down-regulation of PERK signaling in response to endoplasmic reticulum stress" RELATED
    "down-regulation of PERK-mediated unfolded protein response" EXACT
    "down-regulation of PKR-like ER kinase signal transduction" EXACT
    "down-regulation of UPR signaling by PERK stress sensor" EXACT
    "downregulation of endoplasmic reticulum unfolded protein response; PERK signaling" EXACT
    "downregulation of PERK branch of UPR" EXACT
    "downregulation of PERK signaling in response to endoplasmic reticulum stress" RELATED
    "downregulation of PERK-mediated unfolded protein response" EXACT
    "downregulation of PKR-like ER kinase signal transduction" EXACT
    "downregulation of UPR signaling by PERK stress sensor" EXACT
    "inhibition of endoplasmic reticulum unfolded protein response; PERK signaling" NARROW
    "inhibition of PERK branch of UPR" NARROW
    "inhibition of PERK signaling in response to endoplasmic reticulum stress" RELATED
    "inhibition of PERK-mediated unfolded protein response" NARROW
    "inhibition of PKR-like ER kinase signal transduction" NARROW
    "inhibition of UPR signaling by PERK stress sensor" NARROW
    "negative regulation of EIF2AK3-mediated unfolded protein response" RELATED
    "negative regulation of endoplasmic reticulum unfolded protein response; PERK signaling" EXACT
    "negative regulation of PERK branch of UPR" EXACT
    "negative regulation of PERK signaling in response to endoplasmic reticulum stress" RELATED
    "negative regulation of PKR-like ER kinase signal transduction" EXACT
    "negative regulation of UPR signaling by PERK stress sensor" EXACT
Secondary IDs
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