FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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Term negative regulation of blood-brain barrier permeability ID (Ontology) GO:1905604 (Gene Ontology)
Definition Any process that decreases blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain.[ PubMed:22524708 PubMed:30280653 ]
Also Known As "down-regulation of BBB permeability" ; "down-regulation of blood-brain barrier permeability" ; "down-regulation of blood/brain barrier permeability" (for all, see Synonyms field below)
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regulation of vascular permeability
 |__negative regulation of vascular permeability____
 |__regulation of blood-brain barrier permeability__|
                                                    negative regulation of blood-brain barrier permeability
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Is a negative regulation of vascular permeability
regulation of blood-brain barrier permeability
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Synonyms
  • "down-regulation of BBB permeability" EXACT
    "down-regulation of blood-brain barrier permeability" EXACT
    "down-regulation of blood/brain barrier permeability" EXACT
    "downregulation of BBB permeability" EXACT
    "downregulation of blood-brain barrier permeability" EXACT
    "downregulation of blood/brain barrier permeability" EXACT
    "inhibition of maintenance of permeability of BBB" NARROW
    "inhibition of maintenance of permeability of blood-brain barrier" NARROW
    "negative regulation of BBB permeability" EXACT
    "negative regulation of blood/brain barrier permeability" EXACT
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