General Information
Term	primosome complex	ID (Ontology)	GO:1990077 (Gene Ontology)
Definition	Any of a family of protein complexes that form at the origin of replication or stalled replication forks and function in replication primer synthesis in all organisms. Early complexes initiate double-stranded DNA unwinding. The core unit consists of a replicative helicase and a primase. The helicase further unwinds the DNA and recruits the polymerase machinery. The primase synthesizes RNA primers that act as templates for complementary stand replication by the polymerase machinery. The primosome contains a number of associated proteins and protein complexes and contributes to the processes of replication initiation, lagging strand elongation, and replication restart.[ PubMed:21856207 ]
Also Known As	"primosome"
Comment
Links to External Ontologies
	QuickGO data AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
No relevant records available
Records annotated with this exact term (annotations to child terms are NOT included)
No relevant records available
Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
No relevant statements available

General Information

Term

primosome complex

ID (Ontology)

GO:1990077 (Gene Ontology)

Definition

Any of a family of protein complexes that form at the origin of replication or stalled replication forks and function in replication primer synthesis in all organisms. Early complexes initiate double-stranded DNA unwinding. The core unit consists of a replicative helicase and a primase. The helicase further unwinds the DNA and recruits the polymerase machinery. The primase synthesizes RNA primers that act as templates for complementary stand replication by the polymerase machinery. The primosome contains a number of associated proteins and protein complexes and contributes to the processes of replication initiation, lagging strand elongation, and replication restart.[ PubMed:21856207 ]

Also Known As

"primosome"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

No relevant statements available

replication fork
 |__replisome_______________
protein-containing complex  |
 |__protein-DNA complex_____|
protein-DNA complex         |
 |__replisome_______________|
                            primosome complex
                             |__core primosome complex
                             |   |__DnaB-DnaG complex
                             |__DnaA-DiaA complex
                             |__DnaA-HU complex
                             |__DnaA-oriC complex
                             |__DnaB-DnaC complex
                             |__pre-primosome complex
                                 |__DnaA-DnaB-DnaC complex
                                 |__DnaB-DnaC-DnaT-PriA-PriB complex
                                 |__DnaB-DnaC-DnaT-PriA-PriC complex
                                 |__DnaB-DnaC-Rep-PriC complex

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Relationships
Is a	protein-DNA complex
Part of	replisome
Synonyms & Secondary IDs
Synonyms
	"primosome" EXACT
Secondary IDs

External Crossreferences & Linkouts

Spanning Tree View Settings

Parents/Children
View Depth

Relationships

Is a

protein-DNA complex

Part of

replisome

Synonyms & Secondary IDs

Synonyms

"primosome" EXACT

Secondary IDs

External Crossreferences & Linkouts