Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
No relevant statements available
| General Information | |||
|---|---|---|---|
| Term | STING complex | ID (Ontology) | GO:1990231 (Gene Ontology) |
| Definition | A protein dimer containing two STING monomers. It binds cyclic purine di-nucleotides. Activation of the sting complex by 2',5'-3'-5'-cyclic GMP-AMP activates nuclear transcription factor kB (NF-kB) and interferon regulatory factor 3 (IRF3) which then induce transcription of the genes encoding type I IFN and cytokines active in the innate immune response.[ PubMed:22705373 PubMed:23706668 PubMed:23910378 ] | ||
| Also Known As | "stimulator of interferon genes complex" | ||
| Comment | |||
| Links to External Ontologies | |||
| QuickGO data AmiGO data | |||
| Annotations | |||
| Records annotated with this term OR any of its CHILD TERMS | |||
|
Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
|
|||
|
No relevant statements available
|
|||
|
|||||||
vesicle membrane |__cytoplasmic vesicle membrane__ membrane | |__membrane protein complex______| cytoplasmic vesicle | |__cytoplasmic vesicle membrane__| protein-containing complex | |__membrane protein complex______| STING complex |
| Spanning Tree View Settings | |||
|---|---|---|---|
| Parents/Children View Depth |
|||
Relationships
|
|||
| Is a | membrane protein complex | ||
| Part of | cytoplasmic vesicle membrane | ||
|
Synonyms & Secondary IDs
|
|||
| Synonyms | |||
|
|||
| Secondary IDs | |||
|
|
|||
|
External Crossreferences & Linkouts
|
|||
