FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term snRNA 2,2,7-trimethylguanosine (TMG) capping ID (Ontology) GO:1990273 (Gene Ontology)
Definition The sequence of enzymatic reactions by which a 2,2,7-trimethylguanosine cap structure is added to the 5' end of an snRNA. The snRNA capping process includes the formation of 7-methyl-G caps found on all RNA polymerase II transcripts, followed by hypermethylation at the 2' position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. Note that the pol III transcribed U6 snRNA is also TMG capped.[ PubMed:15590684 ]
Also Known As "snRNA 2,2,7-trimethylguanosine (TMG) cap formation" ; "snRNA capping"
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RNA 5'-end processing
 |__RNA capping__________
RNA processing           |
 |__snRNA processing_____|
snRNA metabolic process  |
 |__snRNA processing_____|
                         snRNA 2,2,7-trimethylguanosine (TMG) capping
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RNA capping
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Synonyms
  • "snRNA 2,2,7-trimethylguanosine (TMG) cap formation" EXACT
    "snRNA 5'-end processing" BROAD
    "snRNA capping" EXACT
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