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| Term | Bfa1-Bub2 complex | ID (Ontology) | GO:1990334 (Gene Ontology) |
| Definition | A protein complex that acts as a two-component GTPase-activating protein for Tem1 GTPase, thus regulating a signal transduction cascade, called the mitotic exit network (MEN), which is required for mitotic exit and cytokinesis. Bub2/Bfa1 keeps Tem1 inactive until the spindle is properly oriented, thus inhibiting MEN activation.[ PubMed:16449187 ] | ||
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microtubule organizing center |__spindle pole body_________ enzyme activator complex | |__GTPase activator complex__| Bfa1-Bub2 complex |
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| Is a | GTPase activator complex | ||
| Part of | spindle pole body | ||
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