FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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Term intrinsic apoptotic signaling pathway in response to nitrosative stress ID (Ontology) GO:1990442 (Gene Ontology)
Definition The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to nitrosative stress; a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.[ PubMed:23985028 ]
Also Known As "nitrosative stress-induced intrinsic apoptotic signaling pathway"
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intracellular signal transduction
 |__intrinsic apoptotic signaling pathway____
response to nitrosative stress               |
 |__cellular response to nitrosative stress__|
cellular response to chemical stress         |
 |__cellular response to nitrosative stress__|
apoptotic signaling pathway                  |
 |__intrinsic apoptotic signaling pathway____|
                                             intrinsic apoptotic signaling pathway in response to nitrosative stress
                                              |__regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway
                                                  |__negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway
                                                  |__positive regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway
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Is a cellular response to nitrosative stress
intrinsic apoptotic signaling pathway
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Synonyms
  • "nitrosative stress-induced apoptosis" RELATED[ PubMed:23985028 ]
    "nitrosative stress-induced intrinsic apoptotic signaling pathway" EXACT
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