FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term raps-insc complex ID (Ontology) GO:1990499 (Gene Ontology)
Definition Protein complex required for the asymmetric division of neuroblasts in Drosophila. Coordinates asymmetric localization of cell fate determinants with orientation of the mitotic spindle resulting in different daughter cells upon division. Localizes at the apical cortex of the neuroblast: Raps maintains, but does not initiate, Insc apically, while Insc segregates Raps asymmetrically. Complex appears to be conserved in mammals (composed of INSC and GPSM1 or GPSM2).[ PubMed:22171003 ]
Also Known As "partner of inscuteable-inscuteable complex" ; "Rapsynoid-Inscuteable complex"
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       2
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Relevant FlyBase reports
 Gene Groups Genes
 raps-insc complex (all annotations which use CV term, excluding "NOT" statements)       1      2
     part_of | raps-insc complex       --       2
Spanning Tree (Parents/Children)
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cellular_component
 |__protein-containing complex__
apical part of cell             |
 |__apical cortex_______________|
cell cortex region              |
 |__apical cortex_______________|
                                raps-insc complex  3 rec.
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Is a protein-containing complex
Part of apical cortex
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Synonyms
  • "partner of inscuteable-inscuteable complex" EXACT
    "Rapsynoid-Inscuteable complex" EXACT
Secondary IDs
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