FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
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Term dense core granule maturation ID (Ontology) GO:1990502 (Gene Ontology)
Definition Steps required to transform a dense core granule generated at the trans-Golgi network into a fully formed and transmissible dense core granule. Dense core granule maturation proceeds through clathrin-mediated membrane remodeling events and is essential for efficient processing of cargo within dense core granules as well as for removing factors that might otherwise interfere with dense core granule trafficking and exocytosis.[ PubMed:22654674 ]
Also Known As "dense core vesicle maturation"
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secretory granule organization___
anatomical structure maturation__|
                                 secretory granule maturation
                                  |__dense core granule maturation
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