FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term dense core granule exocytosis ID (Ontology) GO:1990504 (Gene Ontology)
Definition The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense core granule by fusion of the granule with the plasma membrane of a cell in response to increased cytosolic calcium levels.[ PubMed:17553987 PubMed:24653208 ]
Also Known As "dense core vesicle exocytosis"
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       1
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Relevant FlyBase reports
 Genes
 dense core granule exocytosis (all annotations which use CV term, excluding "NOT" statements)       1
     involved_in | dense core granule exocytosis       1
Spanning Tree (Parents/Children)
Only view relationship: 
secretory granule localization
 |__dense core granule localization________
regulated exocytosis                       |
 |__calcium-ion regulated exocytosis_______|
vesicle localization                       |
 |__establishment of vesicle localization__|
establishment of localization in cell      |
 |__establishment of vesicle localization__|
establishment of organelle localization    |
 |__establishment of vesicle localization__|
                                           dense core granule exocytosis  5 rec.
                                            |__dense core granule docking
                                            |__dense core granule priming 1 rec.
                                            |__neuronal dense core vesicle exocytosis 3 rec.
                                            |   |__postsynaptic dense core vesicle exocytosis(+)
                                            |   |__presynaptic dense core vesicle exocytosis(+) 3 rec.
                                            |__regulation of dense core granule exocytosis 1 rec.
                                                |__negative regulation of dense core granule exocytosis
                                                |__positive regulation of dense core granule exocytosis
                                                |__regulation of postsynaptic dense core vesicle exocytosis
                                                |__regulation of presynaptic dense core granule exocytosis 1 rec.
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Is a calcium-ion regulated exocytosis
dense core granule localization
establishment of vesicle localization
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Synonyms
  • "dense core vesicle exocytosis" EXACT
Secondary IDs
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